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Because HPVs are not thought to enter the blood stream, having an HPV infection in one part of the body should not cause an infection in another part of the body.

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Areas not covered by a condom can be infected with the virus, though, so condoms are unlikely to provide complete protection against virus spread.The Food and Drug Administration (FDA) has approved two HPV vaccines: Gardasil® for the prevention of cervical, anal, vulvar, and vaginal cancer, as well as precancerous lesions in these tissues and genital warts caused by HPV infection; and Cervarix® for the prevention of cervical cancer and precancerous cervical lesions caused by HPV infection.Some HPV infections, however, can persist for many years.Persistent infections with high-risk HPV types can lead to more serious cytologic abnormalities or lesions that, if untreated, may progress to cancer. These cells, which are organized in layers, cover the inside and outside surfaces of the body, including the skin, the throat, the genital tract, and the anus.HPV, also called human papillomavirus, is a group of more than 150 related viruses.

More than 40 of these viruses can be easily spread through direct skin-to-skin contact during vaginal, anal, and oral sex.

In the United States, more than half of the cancers diagnosed in the oropharynx are linked to HPV-16.

The incidence of HPV-associated oropharyngeal cancer has increased during the past 20 years, especially among men.

HPV types 16 and 18 have also been found to cause close to half of vaginal, vulvar, and penile cancers.

Most recently, HPV infections have been found to cause cancer of the oropharynx, which is the middle part of the throat including the soft palate, the base of the tongue, and the tonsils.

HPV infections are the most common sexually transmitted infections in the United States.