Other genes also may play a role in the severity of the disease.
Every person inherits two CFTR genes -- one from each parent.
This can upset the balance of minerals in your blood and cause many health problems.
Examples of these problems include dehydration (a lack of fluid in your body), increased heart rate, fatigue (tiredness), weakness, decreased blood pressure, heat stroke, and, rarely, death.
They're related to how CF affects the respiratory, digestive, or reproductive systems of the body. The widened airway is blocked by thick, sticky mucus that contains blood and bacteria.
Figure A shows the organs that cystic fibrosis can affect. People who have CF have thick, sticky mucus that builds up in their airways.
Cystic fibrosis (SIS-tik fi-BRO-sis), or CF, is an inherited disease of the secretory (see-KREH-tor-ee) glands.
Secretory glands include glands that make mucus and sweat.
The thick, sticky mucus also can block tubes, or ducts, in your pancreas (an organ in your abdomen).
As a result, the digestive enzymes that your pancreas makes can't reach your small intestine. Without them, your intestines can't fully absorb fats and proteins.
The disease is less common among African Americans and Asian Americans. One of the first signs of CF that parents may notice is that their baby's skin tastes salty when kissed, or the baby doesn't pass stool when first born.
More than 10 million Americans are carriers of a faulty CF gene. The signs and symptoms of cystic fibrosis (CF) vary from person to person and over time. Most of the other signs and symptoms of CF happen later.
Children who inherit a faulty CFTR gene from each parent will have CF.